The Applied Biology & Chemistry Journal (TABCJ)

ISSN: 2582-8789 (online)

Immunohistochemistry as an important tool for exploring the insights of various aspects of gastro-intestinal tract

Ritesh Kumar Shukla

Department of Zoology, St. Xavier's College, Ranchi, Jharkhand, India

N Venkat Appa Rao*

Department of Zoology, St. Xavier's College, Ranchi, Jharkhand, India


25 December 2020


The concepts in immunology and techniques in histology have come together in a novel way to create a pioneering discipline known as ImmunoHistoChemistry (IHC), to discover new ways in detecting cell and tissue antigens related to amino acids, proteins and infectious agents by using labeled antibodies. These amalgamation techniques are applied in the disciplines of endocrinology, entero-biology, neurobiology, pathology, tumor biology and pharmaceutical research as a diagnostic tool. The simultaneous advancements in the field of imaging techniques further assisted and widened the application of IHC in molecular studies, thereby facilitating the development of novel therapeutic strategies. This paper attempts to discuss the different aspects of gastro-intestinal tract in relation to its cellular diversity, cellular differentiation, physiology and pathology, through the application of IHC methods.


cell identification; cellular diversity; gastro-intestinal tract; immunohistochemistry

Cite this article

Shukla RK, Rao NVA (2020). Immunohistochemistry is an important tool for exploring the insights of various aspects of gastro-intestinal tract. T. Appl. Biol. Chem. J; 1(2):72-82.

Citation: 1


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Copyright: © 2020 Ritesh Kumar Shukla & N Venkat Appa Rao. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.